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040 |a Gr-KaHUA  |b gre  |e AACR2 
041 0 |a eng 
082 0 |a 615.19 
245 0 0 |a Molecular biology in medicinal chemistry/  |c edited by Th. Dingermann, D. Steinhilber and G. Folkers 
260 |a Weinheim:  |b Wiley-VCH,  |c c2004 
300 |a xxi, 413 σ. :  |b εικ. ;  |c 25 εκ. 
490 0 |a Methods and principles in medicinal chemistry  |v 21 
504 |a Περιέχει βιβλιογραφικές παραπομπές και ευρετήριο 
505 0 |a Part I. Molecular targets -- 1. Cellular assays in drug discovery -- 2. Gene knockout models -- 3. Reporter gene assay system for the investigation of G-protein-coupled receptors -- 4. From the human genome to new drugs: the potential of orphan G-protein-coupled receptors -- Part II. Synthesis -- 5. Stereoselective synthesis with the help of recombinant enzymes -- 6. Nucleic acid drugs -- Part III. Analysis -- 7. Recent trends in enantioseperation of chiral drugs -- 8. Affinity chromatography -- 9. Nucleic magnetic resonance-based drug discovery -- 10. C-and N-Isotopic labeling of proteins -- 11. Application of antibody fragments as crystallization enhancers -- Part IV. Kinetics, metabolism and toxicology -- 12. Pharmacogenetics: the effect of inherited genetic variation on drug disposition and drug response -- 13. Pharmacogenemics of biovailability and elimination -- 14. Toxicogenomics: integration of new molecular biological tools in toxicology -- Index 
650 1 7 |a Μοριακή φαρμακολογία 
650 1 7 |a Φαρμακοχημεία 
650 1 7 |a Φαρμακογονιδιωματική 
650 1 7 |a Γονιδιωματική 
650 1 0 |a Molecular pharmacology 
650 1 0 |a Pharmaceutical chemistry 
650 1 0 |a Pharmacogenomics 
650 1 0 |a Genomics 
700 1 |a Dingermann, Theodor 
700 1 |a Steinhilber, Dieter, 
700 1 |a Folkers, Gerd 
952 |a GR-KaHUA  |b 59cca54c6c5ad13446031289  |c 998a  |d 945l  |e 615.19 MOL  |t 1  |x m  |z Books