Table of Contents: Sequence alignment :

Other Authors:	Rosenberg, Michael S.,
Format:	Book
Language:	English
Subjects:	Bioinformatics. Computational biology.
Online Access:	http://site.ebrary.com/lib/ucy/Doc?id=11047669

Table of Contents:

Sequence alignment : concepts and history
Insertion and deletion events, their molecular mechanisms, and their impact on sequence alignments
Local versus global alignments
Computing multiple sequence alignment with template-based methods
Sequence evolution models for simultaneous alignment and phylogeny reconstruction
Phylogenetic hypotheses and the utility of multiple sequence alignment
Structural and evolutionary considerations for multiple sequence alignment of RNA, and the challenges for algorithms that ignore them
Constructing alignment benchmarks
Simulation approaches to evaluating alignment error and methods for comparing alternate alignments
Robust inferences from ambiguous alignments
Strategies for efficient exploitation of the informational content of protein multiple alignments.