Sequence alignment : methods, models, concepts, and strategies /

Other Authors: Rosenberg, Michael S.,
Format: Book
Language:English
Subjects:
Online Access:http://site.ebrary.com/lib/ucy/Doc?id=11047669
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245 0 0 |a Sequence alignment :  |b methods, models, concepts, and strategies /  |c edited by Michael S. Rosenberg. 
300 |a 1 online resource (357 pages) :  |b illustrations 
504 |a Includes bibliographical references (pages 297-332) and index. 
505 0 |a Sequence alignment : concepts and history -- Insertion and deletion events, their molecular mechanisms, and their impact on sequence alignments -- Local versus global alignments -- Computing multiple sequence alignment with template-based methods -- Sequence evolution models for simultaneous alignment and phylogeny reconstruction -- Phylogenetic hypotheses and the utility of multiple sequence alignment -- Structural and evolutionary considerations for multiple sequence alignment of RNA, and the challenges for algorithms that ignore them -- Constructing alignment benchmarks -- Simulation approaches to evaluating alignment error and methods for comparing alternate alignments -- Robust inferences from ambiguous alignments -- Strategies for efficient exploitation of the informational content of protein multiple alignments. 
650 0 |a Bioinformatics. 
650 0 |a Computational biology. 
700 1 |a Rosenberg, Michael S., 
856 4 0 |u http://site.ebrary.com/lib/ucy/Doc?id=11047669 
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