Mass spectrometry in drug metabolism and disposition basic principles and applications /
| Corporate Author: | |
|---|---|
| Other Authors: | |
| Format: | Book |
| Language: | English |
| Published: |
Hoboken, N.J. :
John Wiley & Sons,
c2011.
|
| Series: | Wiley series on pharmaceutical science and biotechnology: practices, applications and methods
|
| Subjects: | |
| Online Access: | http://site.ebrary.com/lib/ucy/Doc?id=10456208 |
Table of Contents:
- (Publisher-supplied data) Part I Basic Concepts of Drug Metabolism and Disposition
- The Progression of Drug Metabolism
- Common Biotransformation Reactions
- Metabolic Activation of Organic Functional Groups Utilized in Medicinal Chemistry
- Drug Metabolizing Enzymes, Transporters and Drug-Drug Interactions
- Experimental Models of Drug Metabolism and Disposition
- Principles of Pharmacokinetics: Predicting Human Pharmacokinetics
- Drug Metabolism Research as an Integral Part of the Drug Discovery and Development Processes
- Part II Mass Spectrometry in Drug Metabolism: Principles and Common Practice
- Theory and Instrumentation of Mass Spectrometry
- Common Liquid Chromatography-Mass Spectrometry (LC-MS) Methodology for Metabolite Identification
- Mass Spectral Interpretation
- Techniques to Facilitate the Performance of Mass Spectrometry: Sample Preparation, Liquid Chromatography and Non-Mass Spectrometric Detection
- Part III Applications of New LC/MS Techniques in Drug Metabolism and Disposition
- Quantitative In Vitro ADME Assays using LC-MS as a Part of Early Drug Metabolism Screening
- High Resolution Mass Spectrometry and Drug Metabolite Identification
- Distribution Studies of Drugs and Metabolites in Tissue by Mass Spectrometric Imaging
- Use of Triple Quadrupole-Linear Ion Trap Mass Spectrometry as a Single LC/MS Platform in Drug Metabolism and Pharmacokinetics Studies
- Quantitative Drug Metabolism with Accelerator Mass Spectrometry
- Standard-Free Estimation of Metabolite Levels Using Nanospray Mass Spectrometry: Current Statutes and Future Directions
- Profiling and Characterization of Herbal Medicine and their Metabolites using LC-MS
- Liquid Chromatography Mass Spectrometry Bioanalysis of Proteins in Biological Matrices
- Mass Spectrometry in the Analysis of DNA, Protein, Peptide, and Lipid Biomarkers of Oxidative Stress
- LC-MS in Endogenous Metabolite Profiling and Small Molecule Biomarker Discovery.