Table of Contents:
  • Cellular assays in drug discovery
  • Gene knockout models
  • Reporter gene assay systems for the investigation of G-proteincoupledReceptors
  • From the human genome to new drugs: The potential of orphan G-proteincoupledReceptors
  • Stereoselective synthesis with the help of recombinant enzymes
  • Nucleic acid drugs
  • Recent trends in enantioseparation of chiral drugs
  • Affinity chromatography
  • Nuclear magnetic resonance-based drug discovery
  • 13C- and 15N-Isotopic labeling of proteins
  • Application of antibody fragments as crystallization enhancers
  • Pharmacogenetics: the effect of inherited genetic variation on drug disposition and drug response
  • Pharmacogenomics of bioavailability and elimination