Surgical research /

Other Authors: Souba, Wiley W.
Format: Book
Language:English
Published: San Diego, CA : Academic Press, 2001.
Subjects:
Online Access:http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=240245
Table of Contents:
  • Contributors.
  • Foreword.
  • Preface.
  • Getting Started.
  • Assessing Available Information.
  • Organizing and Preliminary Planning for Surgical Research
  • Writing a Protocol: Animals, Humans, and Use of Biologic, Chemical, and Radiologic Agents.
  • Grantsmanship.
  • Informed Consent and the Protection of Human Research Subjects: Historical Perspectives and Guide to Current United States Regulations.
  • Animal Care and Maintenance.
  • Funding Strategies and Agencies: Academic-Industrial Relationships; Intellectual Property.
  • Statistical Considerations.
  • Use of Nonexperimental Studies to Evaluate Surgical Procedures and Other Interventions: The Challenge of Risk Adjustment.
  • Measuring Surgical Outcomes.
  • Design of Clinical Trials.
  • Using Administrative Data for Clinical Research.
  • Research in the Intensive Care Unit: Ethical and Methodological Issues.
  • Research in the Operating Room.
  • Effects of Age and Gender.
  • Strategies, Principles, and Techniques Using Transgenic and Knockout Mouse Models.
  • Tissue Culture, Cell Growth, and Analysis.
  • Hematopoietic Stem Cells: Basic Concepts and Applications to Surgical Research.
  • Base Molecular Biological Methods in Surgical Research: Genetic Library Construction, Screening, and DNA Sequencing.
  • Transcription.
  • Signal Transduction and Apoptosis.
  • Mechanisms and Regulation of Eukaryotic Protein Synthesis.
  • Organelle Studies: Mitochondria, Golgi, and Endoplasmic Reticulum.
  • Membrane Biology and Biophysics.
  • Molecular Epidemiology: Beyond Gene Discovery to Clinical Diagnostic Tools.
  • Shock Models: Hemorrhage.
  • Scoring Systems for Trauma Research.
  • Blunt Trauma Models: Fractures, Chest Trauma, Head Injury, Soft-Tissue Trauma, and Abdominal Trauma.
  • Trauma Models for Studying the Influence of Gender and Aging.
  • Animal Models of Burn Injury.
  • Wound Care Models.
  • Models of Adult Respiratory Distress Syndrome-Aspiration.
  • Tumor Angiogenesis.
  • Approaches to Adoptive Immunotherapy.
  • Metastasis: Biology and Experimental Models.
  • Cancer Genetics.
  • Cancer Gene Therapy.
  • Active Immunotherapy for Cancer.
  • Gastrointestinal Motility.
  • Models of Intestinal Secretion and Absorption.
  • Surgical Models of Inflammatory Bowel Disease.
  • Intestinal Regeneration and Adaptation Models.
  • Minimally Invasive Surgery.
  • Experimental Models and Endpoints for Studies of Intestinal Ischemia-Resperfusion Injury.
  • Gut Barrier Failure.
  • Developmental Studies in the Gastrointestinal Tract.
  • Animal Models of Liver Failure.
  • Portal Hypertension and Portacaval Shunt.
  • Animal Models of Liver Regeneration.
  • Animal Models for the Study of Hepatocyte Transplantation.
  • Biliary Stone Formation.
  • Models for the Study of Pancreatitis.
  • Models of Endocrine Insufficiency.
  • Animal Models in Transplantation.
  • Models to Study Surgical Nutrition and Metabolism.
  • Stable Isotopes.
  • Body Composition.
  • Energetics.
  • Models of Protein Metabolism.
  • Membrane Transport of Nutrients.
  • Models of Wound Healing in Growth Factor Studies.
  • Animal Models of Sepsis and the Multiple Organ Dysfunction Syndrome.
  • The Immuno-Inflammatory Response.
  • Antibiotic Trials.
  • Scoring Systems for Sepsis and the Multiple Organ Dysfunction Syndrome.
  • Cytokine Biology.
  • Biology of Nitric Oxide: Measurement, Modulation, and Models.
  • Endothelial Cell and Smooth Muscle Cell Biology in Vascular Disease.
  • Coagulation Biology.
  • Endovascular Research: Stents.
  • Noninvasive Vascular Measurements.
  • Techniques to Study Microcirculation.
  • Blood Substitutes in Surgery.
  • Research Models in Pediatric Surgery.
  • Research in Fetal Surgery.
  • Research in Plastic Surgery.
  • Research Methods in Neurosurgery.
  • Research in Urologic Surgery.
  • Research in Cardiac Surgery.
  • Research in Orthopedic Surgery.
  • Statistical Analysis-Specific Statistical Tests: Indications for Use.
  • Data Presentation: How to Write and Submit Abstracts and Papers.
  • Audiovisual Communications as a Research Skill.
  • Organizing and Managing Meetings and Conferences.
  • The Management and Organization of a Surgical Research Laboratory.
  • History and Philosophy of Surgical Research.
  • The Surgical Research Program as a Business Enterprise.
  • Nobel Laureates in Surgery.
  • Surgical Education Research.
  • Mathematical Modeling.
  • Information Resource Discovery for Surgeons: Databases and the Internet.
  • How to Review a Manuscript.
  • Academic Surgical Mentoring.
  • Ethics and Surgical Research.
  • The National Institutes of Health: Procedures and Performance.
  • Measuring the Performance of Surgical Research.
  • Virtual Reality and Surgery.
  • Surgeons and Health Services Research.
  • From Idea to Product: Financing and Regulatory Issues in Product Development.