Table of Contents:
  • 1 INTRODUCTION
  • 2 SPECTRUM OF MICROBIAL THREATS
  • The Global Burden of AIDS, Tuberculosis, and Malaria, 25
  • Emerging Infectious Diseases, 32
  • Antimicrobial-Resistant Infections, 32
  • Chronic Diseases with Infectious Etiology, 41
  • Microbes Intentionally Used for Harm, 46
  • 3 FACTORS IN EMERGENCE
  • Microbial Adaptation and Change, 53
  • Human Susceptibility to Infection, 60
  • Climate and Weather, 64
  • Changing Ecosystems, 67
  • Economic Development and Land Use, 75
  • Human Demographics and Behavior, 78
  • Technology and Industry, 88
  • International Travel and Commerce, 97
  • Breakdown of Public Health Measures, 107
  • Poverty and Social Inequality, 121
  • War and Famine, 125
  • Lack of Political Will, 127
  • Intent to Harm, 130
  • A Case in Point: Influenza-We Are Unprepared, 136
  • 4 ADDRESSING THE THREATS: CONCLUSIONS AND RECOMMENDATIONS
  • Enhancing Global Response Capacity, 149
  • Improving Global Infectious Disease Surveillance, 154
  • Rebuilding Domestic Public Health Capacity, 159
  • Improving Domestic Surveillance Through Better Disease Reporting, 163
  • Exploring Innovative Systems of Surveillance, 170
  • Developing and Using Diagnostics, 174
  • Educating and Training the Microbial Threat Workforce, 181
  • Vaccine Development and Production, 184
  • Need for New Antimicrobial Drugs, 190
  • Inappropriate Use of Antimicrobials, 204
  • Vector-borne and Zoonotic Disease Control, 209
  • Comprehensive Infectious Disease Research Agenda, 220
  • Interdisciplinary Infectious Disease Centers, 222.