Emerging drugs and targets for alzheimer's disease.

Other Authors: Martinez, Ana.
Format: Book
Language:English
Published: Cambridge, Royal Society of Chemistry, 2010.
Subjects:
Online Access:http://dx.doi.org/10.1039/9781849731065
Table of Contents:
  • Beta-Amyloid as target
  • Chapter 1: The amyloid hypothesis of AD and prospects for therapeutics
  • Chapter 2: Targeting Alzheimer's ?-Secretase: Genetic and Chemical Modulation
  • Chapter 3: Cholesterol and AD: the molecules, the targets
  • Chapter 4: The Bimodal Features of Butyrylcholinesterase in Cholinergic Neurotransmission and Amyloid Suppression
  • Chapter 5: Scyllo-inositol, a potential therapy for Alzheimer's disease
  • Chapter 6: Immunotherapeutic strategies toward treatment of AD
  • Tau protein as target
  • Chapter 7: Alzheimer Neurofibrillary Degeneration: Pivotal Role and Therapeutic Targets
  • Chapter 8: Multiple roles of glycogen synthase kinase-3 in AD
  • Chapter 9: Tau protein kinases inhibitors: from the bench to the clinical trials
  • Chapter 10: Activating PP2A as a therapeutic intervention strategy in AD
  • Chapter 11: Rationale for tau aggregation inhibitor therapy in Alzheimer's disease and other tauopathies
  • Glucose Metabolism as target
  • Chapter 12: Insulin Insulin Resistance and neurodegeneration: Type 2 versus type 3 diabetes mellitus
  • Chapter 13: Insulin-like Growth Factor I as a disease-modifying therapy in Alzheimer's disease
  • Chapter 14: Ketone bodies as a therapeutic for Alzheimer's disease.