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20171111234632.0 |
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100706s2011 njuaf sb 001 0 eng d |
| 020 |
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|z 9780470499467 (cloth)
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|a CaPaEBR
|z 9780470933930 (e-book)
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| 050 |
1 |
4 |
|a RB155
|b .G3584 2011eb
|
| 245 |
0 |
0 |
|a Gene discovery for disease models
|c edited by Weikuan Gu.
|
| 260 |
|
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|a Hoboken, N.J. :
|b Wiley,
|c c2011.
|
| 300 |
|
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|a xiii, 537 p., [15] p. of plates :
|b col. ill.
|
| 504 |
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|a Includes bibliographical references and index.
|
| 505 |
0 |
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|a Introduction : gene discovery-from positional cloning to genomic cloning -- High throughput gene expression analysis and the identification of expression QTLs -- DNA methylation in the pathogenesis of autoimmunity -- Ccell-based analysis with microfluidic chip -- Missing dimension : protein turnover rate measurement in gene discovery -- Bioinformatics tools for the prediction of gene function -- Determination of genomic locations of targeted genetic loci -- Mutation discovery using high throughput mutation screening technology -- Candidate screening through gene expression profile -- Candidate screening through high-density SNP array -- Gene discovery through direct genome sequencing -- Candidate screening through bioinformatics tools -- Using an integrative strategy to identify mutations -- Determination of the function of a mutant in a gene -- Confirmation of a mutation by multiple molecular approaches -- Confirmation of a mutation by microRNA -- Confirmation of function of a gene by translational approaches -- Confirmation of single nucleotide mutations -- Initial identification and confirmation of a QTL gene -- Gene discovery of crop diseases in the post genome era -- Impact of whole genome genetic element analysis on gene discovery of disease models -- Impact of whole genome protein analysis on gene discovery of disease models.
|
| 650 |
|
0 |
|a Medical genetics.
|
| 650 |
|
0 |
|a Mutation (Biology)
|
| 650 |
|
0 |
|a Genomics.
|
| 700 |
1 |
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|a Gu, Weikuan.
|
| 710 |
2 |
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|a ebrary, Inc.
|
| 856 |
4 |
0 |
|u http://site.ebrary.com/lib/ucy/Doc?id=10441397
|
| 952 |
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|a CY-NiOUC
|b 5a045f7e6c5ad14ac1edfbc4
|c 998a
|d 945l
|e -
|t 1
|x m
|z Books
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