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| LEADER |
01545nam a2200217 a 4500 |
| 001 |
1798533 |
| 005 |
20171111234544.0 |
| 008 |
120224s2012 njua sb 001 0 eng d |
| 020 |
|
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|z 9781118188330 (cloth)
|z 9781118028681 (cloth)
|
| 040 |
|
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|a CaPaEBR
|z 9781118354315 (e-book)
|
| 050 |
1 |
4 |
|a RM301.4
|b .S84 2012eb
|
| 100 |
1 |
|
|a Sugano, Kiyohiko.
|
| 245 |
1 |
0 |
|a Biopharmaceutics modeling and simulations
|b theory, practice, methods, and applications /
|c Kiyohiko Sugano.
|
| 260 |
|
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|a Hoboken, N.J. :
|b Wiley,
|c c2012.
|
| 300 |
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|a xxxv, 483 p. :
|b ill.
|
| 504 |
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|a Includes bibliographical references and index.
|
| 505 |
0 |
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|a Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice.
|
| 650 |
|
0 |
|a Biopharmaceutics
|x Simulation methods.
|
| 710 |
2 |
|
|a ebrary, Inc.
|
| 856 |
4 |
0 |
|u http://site.ebrary.com/lib/ucy/Doc?id=10583403
|
| 952 |
|
|
|a CY-NiOUC
|b 5a0459386c5ad14ac1ed2c16
|c 998a
|d 945l
|e -
|t 1
|x m
|z Books
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