Kallikrein-related peptidases

Corporate Author: ebrary, Inc.
Other Authors: Magdolen, Viktor.
Format: Book
Language:English
Published: Berlin : Walter de Gruyter, c2012.
Subjects:
Online Access:http://site.ebrary.com/lib/ucy/Doc?id=10649214
Table of Contents:
  • Genomic structure of the KLK locus
  • Single nucleotide polymorphisms in the human KLK locus and their implication in various diseases
  • Evolution of Kallikrein-related peptidases
  • Structural aspects of Kallikrein-related peptidases
  • Molecular recognition properties of Kallikrein-related peptidases on synthetic and endogenous substrates
  • Natural, engineered, and synthetic inhibitors of Kallikrein-related peptidases
  • Kallikrein-related peptidases as pharmaceutical targets
  • Expression of Kallikrein-related peptidases under (patho) physiological conditions
  • Kallikrein-related peptidases within the proteolytic web
  • Kallikrein-Kinin cascade: bioregulation by human tissue kallikrein 1 (HK1, KLK 1)
  • Role of KLK4 in dental enamel formation.
  • Kallikrein-related peptidases and semen
  • Kallikrein-related peptidases and inhibitors of the skin
  • Physiological and pathophysiological roles of Kallikrein-related peptidases in the central nervous system
  • Kallikrein-related peptidases (KLKS), proteinase-mediated signaling and proteinase-activated receptors (PARS)
  • Pathophysiology of Kallikrein-related peptidases in lung cancer
  • Clinical relevance of Kallikrein-related peptidases in gastric and colorectal cancer
  • Pathophysiology of Kallikrein-related peptidases in head and neck cancer
  • PSA (prostate-specific antigen) and other Kallikrein-related peptidases in prostate cancer
  • Cellular model systems to study the tumor biological role of Kallikrein-related peptidases in ovarian and prostate cancer
  • Clinical relevance of Kallikrein-related peptidases in breast cancer
  • Clinical relevance of Kallikrein-related peptidases in ovarian cancer
  • MicroRNAs : a new control mechanism for Kallikrein-related peptidases in kidney and other cancers
  • Genomic instability of the KLK-locus in cancer
  • Kallikrein-related peptidases as biomarkers in personalized cancer medicine.